RIKEN Center for Life Science Technologies


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For Public

To let you know about our research, this area contains 4 types of information about CLST; “Article”, “Videos”, “Event” and “Study”.
At “Article”, you can read articles on interviews and lectures, and you can enjoy the videos about CLST at “Videos”. If you want to meet and talk directly with the researcher, “Visit” give you some information of such events. You can find more difficult contents to know about our research deeply at “Study”.
  • Article
  • Event
  • Videos
  • Study

Labs & Technologies

Structural Biology Group

We aim to develop novel methods for preparation of biomolecules reflecting their dynamic functional states, and operate an integrated structural analysis pipeline, composed of X-ray crystallography, NMR spectroscopy, cryo-electron microscopy and others. By advancing such technologies and methodologies, we will contribute to “life innovation” such as drug development and medical treatment.


We will establish production methods for huge supramolecular complexes consisting of a number of large components that exist in central particles in biological systems, and develop next-generation technologies for micro/nano-crystal structure analyses using SPring-8 (synchrotron radiation)/SACLA (X-ray Free-Electron Laser). It will lead to establishment of a valuable technology platform for supramolecular structure analysis. Using these technologies, we will elucidate the molecular network of intracellular genes, proteins and RNAs at a three-dimensional structure level.

Group Director
Mikako Shirouzu   Ph.D.



CLST was reorganized into three centers according to the RIKEN 4th Medium-Term Plan from April 1, 2018. For the latest information of Structural Biology Group, please visit the following websites.

> Center for Biosystems Dynamics Research [http://www.bdr.riken.jp/en/research/index.html]